Journal of the Acoustical Society of America;118:3953-3960 DOI:10.1121/1.2109167
An ultrasound technique for imaging objects significantly smaller than the source wavelength is investigated. Signals from a focused beam are recorded over an image plane in the acoustic farfield and backprojected in the wave-vector domain to the focal plane. A superresolutionimage recovery method is then used to analyze the Fourier spatial frequency spectrum of the signal in an attempt to deduce the location and size of objects in this plane. The physical foundation for the method is rooted in the fact that high spatial frequencies introduced by the object in fact affect the lower (nonevanescent) spatial frequencies of the overall signal. The technique achieves this by using a priori measurements of the ultrasound focus in water, which gives full spectral information about the image source. A guess is then made regarding the size and location of the object that distorted the field, and this is convolved with the a priori measurement, thus creating a candidate image. A large number of candidates are generated and the one whose spectrum best matches the uncorrected image is accepted. The method is demonstrated using 0.34- and 0.60-mm wires with a focused 1.05-MHzultrasound signal and then a human hair (∼0.03mm) with a 4.7-MHz signal.
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Clinic Ultrasound Laboratory (クレメント超音波研究室)
Cleveland Clinic (クリーブランド・クリニック),
Lerner Research Institute
Case Western Reserve University
© 2013
For a comprehensive listing see PUBLICATIONS
Clement GT, Nomura H, Adachi H, Kamakura T, Feasibility of non-contact ultrasound for medical imaging, Physics in Medicine and Biology 2013; 58: 6263-6278
Tang SC, Jolesz FA, Clement GT. A Wireless Batteryless Implantable Ultrasonic Pulser-Receiver. IEEE Trans Ultrason Ferroelectr Freq Control 2011;58:1211-21.
Paltiel HJ, Padua HM, Gargollo PC, Cannon GM Jr, Alomari AI, Yu R, Clement GT. Volumetric ultrasound imaging of tissue perfusion: preliminary results in a rabbit model... Phys Med Biol 2011;56:2183-97.
McDannold N, Clement GT, Black P, Jolesz F, Hynynen K. Focused ultrasound surgery of brain tumors: Initial findings in three patients. Neurosurgery 2010;66:323-32; discussion 332.
Clement GT, Hynynen K. A non-invasive method for focusing ultrasound through the human skull. Phys Med Biol 2002;47(8):1219-36.